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Rules manual
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Step by step
Game Objective
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Setup
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Game Flow
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Actions and How to Play
The game includes various action cards with specific effects. Each can be used at different times and with its own rules:
Action Cards
- PLACEBO: Use in 2 ways:
- Place this card over any untreated Disorder card to protect it from Episodes for 1 round (does not count as completed treatment).
- Play it when an Episode occurs to nullify it (discard it afterward).
- MUNCHAUSEN BY PROXY: Give any Disorder to another player (except if they already have that Disorder).
- CABINET OF REMEDIES: Take any card from the discard pile.
- REPLENISHMENT: Shuffle the discard pile into the draw pile, then draw cards until you have 6 in your Hand.
- HIGH TOLERANCE: Remove a Drug card from another player's Psyche.
- MISDIAGNOSIS: Swap a Disorder from your Psyche with one from your Hand.
- FOLIE À DEUX: Make a recent Episode affect another player. Can be played outside your turn.
End of Game and Scoring
Refer to the manual for details on this section.
Tips to Win
- Use the Placebo strategically: it can block Episodes, but it is temporary and vulnerable.
- FOLIE À DEUX is powerful outside your turn — share negative effects with opponents.
- Combat others' Drugs with HIGH TOLERANCE to weaken them.
Rules manual
Official PDF file
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Frequently Asked Questions
Quick answers about the rules
What is the objective of Side Effects: Booster Shot?
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How do you set up Side Effects: Booster Shot?
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How do you play Side Effects: Booster Shot?
Refer to the manual for details on this section. The game includes various action cards with specific effects. Each can be used at different times and with its own rules: Action Cards PLACEBO: Use in 2 ways: Place this card over any untreated Disorder card to protect it from Episodes for 1 round (does not count as completed treatment). Play it when an Episode occurs to nullify it (discard it afterward). Tip: The Placebo can treat any Disorder, but it is fragile — if an Episode hits another of…
How does Side Effects: Booster Shot end, and how do you score?
Refer to the manual for details on this section.
What are some tips for winning Side Effects: Booster Shot?
Use the Placebo strategically: it can block Episodes, but it is temporary and vulnerable. FOLIE À DEUX is powerful outside your turn — share negative effects with opponents. Combat others' Drugs with HIGH TOLERANCE to weaken them.
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